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DENTAL MANAGEMENT OF LEUKOCYTE DEFICIENCY IN A CHILD WITH SEVERE ORAL INVOLVEMENT
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±èÇöÁø ( Kim Hyun-Jin ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
À̳¿µ ( Lee Nan-Young ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌ»óÈ£ ( Lee Sang-Ho ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
KMID : 1144020070030010026
Abstract
Àü½ÅÀûÀ¸·Î ¸é¿ªÀÌ °áÇÌµÈ ¹éÇ÷±¸ Á¢Âø °áÇÌÁõ ȯ¾Æ¿¡¼´Â Á¤±âÀûÀÎ ±¸° À§»ý °ü¸®´Â ¸Å¿ì Áß¿äÇÏ´Ù. Ä¡¸é¼¼±Õ¸·ÀÇ Á¦°Å¸¦ ÅëÇØ ±¹¼ÒÀûÀÎ ÀڱؿøÀ» °¨¼Ò½ÃÅ´À¸·Î½á ±¸° ³» Àڱؿ¡ ´ëÇÑ µ¿ÅëÀ̳ª ±¸Ãë °¨¼Ò°¡ °¡´ÉÇÏ°í ÁøÇàµÇ´Â Ä¡ÁÖÁ¶Á÷ÀÇ Æı« ¾ç»óÀ» ¾î´À Á¤µµ Áö¿¬½Ãų ¼ö ÀÖÀ» °ÍÀ¸·Î »ç·áµÈ´Ù. ³»¿øÀ» ÅëÇÑ °ü¸®µµ Áß¿äÇÏÁö¸¸ ÀÕ¼ÖÁú ±³À°À» ÅëÇÏ¿© ȯÀÚ ½º½º·Î °¡Á¤¿¡¼µµ ±¸° À§»ý °ü¸®¸¦ ½ÃÇàÅä·Ï ÇÏ¿©¾ß Çϸç ÇâÈÄ °¨¿°¿øÀÌ µÉ ¼ö ÀÖ´Â ¿øÀÎÀ» °¨¼Ò½ÃÅ°´Â ³ë·ÂÀÌ ÇÊ¿äÇÏ´Ù.
Leukocyte adhesion deficiency(LAD) is a rare autorecessive defect of phagocytic function resulting from a lack of leukocyte cell surface expression of integrin molecules(CD 18) that are essential for leukocyte adhesion to endothelial cells and chemotaxis. As a results, patients with LAD suffer from severe bacterial infections and impaired wound healing. A small number of patients with leukocyte adhesion deficiency-1 have a milder defect, with residual expression of CD18. These patients tend to survive beyond infancy; they manifest progressive severe periodontitis, alveolar bone loss, periodontal pocket formation, and partial or total premature loss of the primary and permanent dentitions. In this report, we report on a 7 year old girl with severe oral involvement. The most import focus should be to control infections to reduce the risk for future infection.
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Leukocyte; Adhesion; Periodontitis
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